Can I take Duromine in hypertension?
Obesity is one of the most important risk factors for hypertension and deterioration of lung function. Duromine promotes weight loss, yet it is important to know whether it can be used in patients with arterial or pulmonary hypertension or not.
Duromine is an adrenergic stimulant and anorectic. The mechanism of its action consists in appetite suppression. However, the drug also has some additional effects, one of which is pressor effect and increased heart rate.
- Increase in blood pressure after intake of Duromine in healthy patients is not clinically significant side effect
However, blood pressure spikes can lead to additional health problems for people with existing hypertension. In addition, patients with autonomic dysfunction are sensitive to action of anorectics, including Duromine.
Obese patients with increased blood pressure should follow a few recommendations while using Duromine:
- to monitor blood pressure changes, especially in the first days of the anorectic use
- not to take the anorectic immediately before the procedure of blood pressure measurement
- to stop using the anorectic if such symptoms as difficulty breathing, chest pain or swelling occur
Only patients with insignificant elevated blood pressure can take Duromine for weight loss. Nevertheless, Duromine is incompatible with adrenergic receptor blockers (including Guanethidine, Clonidine and Methyldopa) that can be used for hypertension treatment.
Use of anorexigenic drugs, such as Duromine, is one of the risk factors for developing pulmonary hypertension.
- Therefore, obese patients with increased blood pressure in the pulmonary artery should avoid Duromine use
Duromine is not recommended for patients with uncontrolled hypertension or a history of heart diseases. Moderate and severe arterial hypertension, as well as pulmonary one are contraindications to the anorectic use.